Dr. Lange's current research interests fall into the broad areas of statistical genetics and generalized linear models. Recent topics in statistical genetics include family-based association tests, meta-analysis of linkage studies, GEE-methods in linkage analysis and marker-assisted selection. In the area of family-based association tests (FBATs), he has focused on the development of power calculations for family-based association studies, multivariate extensions of the FBAT statistic, FBATs for time-to-onset data and approaches to handle the multiple testing problem in family-based studies. Dr. Lange is also involved in collaborative research in asthma genetics and COPD genetics.