Alex Luedtke (Applied Stats Workshop)

Date and Time

October 22, 2025
12:00PM - 01:30PM EDT

Location

CGIS Knafel Building, Room K354

Speaker & Title

Alex Luedtke (University of Washington), "Simplifying debiased inference via automatic differentiation and probabilistic programming"

Abstract

We introduce an algorithm that simplifies the construction of efficient estimators, making them accessible to a broader audience. 'Dimple' takes as input computer code representing a parameter of interest and outputs an efficient estimator. Unlike standard approaches, it does not require users to derive a functional derivative known as the efficient influence function. Dimple avoids this task by applying automatic differentiation to the statistical functional of interest. Doing so requires expressing this functional as a composition of primitives satisfying a novel differentiability condition. Dimple also uses this composition to determine the nuisances it must estimate. In software, primitives can be implemented independently of one another and reused across different estimation problems. We provide a proof-of-concept Python implementation and showcase through examples how it allows users to go from parameter specification to efficient estimation with just a few lines of code.

The Applied Statistics Workshop (Gov 3009) meets all academic year on Wednesdays. This workshop is a forum for advanced graduate students, faculty, and visiting scholars to present and discuss methodological or empirical work in progress in an interdisciplinary setting. The workshop features a tour of Harvard's statistical innovations and applications with weekly stops in different fields and disciplines and includes occasional presentations by invited speakers.

All interested Harvard affiliates are invited to attend. Lunch will be provided.